OCC

Diabetes Outcomes

Diabetes Outcomes Reported in Published MagDI Studies

Published MagDI studies have reported on glycemic control and Type 2 Diabetes-related outcomes in patients undergoing magnetic duodeno-ileostomy, typically combined with sleeve gastrectomy. This page summarizes what the literature describes, with appropriate caveats.

Written by MagnaMetabolic Editorial Team Medically reviewed by Ariel Ortiz, MD — Bariatric & Metabolic Surgery Last reviewed: June 7, 2026

What the published literature reports

  • Improvements in HbA1c and other markers of glycemic control have been reported following Sleeve Plus MagDI at short- and mid-term follow-up.
  • Some patients with Type 2 Diabetes have been reported to achieve reduced medication requirements or, in some cases, diabetes remission as defined by their study's criteria.
  • Outcomes depend on baseline disease severity, duration of diabetes, beta-cell reserve, and adherence to recommended follow-up.

Important caveats

  • Diabetes remission is not the same as a cure. Recurrence is possible, particularly with weight regain or with progression of underlying disease.
  • Long-term durability of diabetes improvement beyond current follow-up windows remains an open research question.
  • Outcomes vary among individuals; published averages should not be interpreted as guarantees.
  • Decisions about diabetes management should always be made in coordination with the treating endocrinologist or diabetes care team.

Context

Metabolic and bariatric surgery is recognized in current ASMBS/IFSO and ADA guidance as an option for selected patients with obesity and Type 2 Diabetes. MagDI and Sleeve Plus MagDI represent newer additions to this field; long-term comparative data with established procedures continue to develop.

Evidence

Scientific References

Selected primary sources informing this page. External links open in a new tab; we do not control or endorse third-party content.

  1. Obesity SurgeryGagner M, et al. First-in-human experience of magnetic duodeno-ileostomy for the treatment of obesity and metabolic disease. Obesity Surgery.
  2. Surgical EndoscopyMulti-center early outcomes of sleeve gastrectomy combined with magnetic duodeno-ileostomy (Sleeve Plus MagDI). Surgical Endoscopy.
  3. ADAAmerican Diabetes Association — Standards of Care in Diabetes (current edition), Section on obesity and metabolic surgery.
  4. ASMBSAmerican Society for Metabolic and Bariatric Surgery (ASMBS) and IFSO 2022 indications for metabolic and bariatric surgery.
  5. ClinicalTrials.govMagDI Chile — A study to evaluate the safety, feasibility, and initial efficacy of the MagDI System in adults with obesity with or without Type 2 Diabetes.
  6. ClinicalTrials.govMagDI Italy — A study to evaluate the safety, performance, and clinical outcomes of the MagDI System.
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